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FASENRA is an add-on maintenance treatment for patients 12 and older with severe eosinophilic asthma. See more

Not for other eosinophilic conditions or sudden breathing problems.

What are eosinophils?

Everyone has eosinophils. They're white blood cells, a normal part of your immune system.

In fact, nearly 7 out of 10 adults with asthma may have elevated eosinophils (e-o-SIN-o-phils)—which can be a key cause of asthma. Too many eosinophils can cause airway inflammation for some people, which can lead to asthma symptoms and attacks. FASENRA is designed to target and remove eosinophils.

The mechanism of action of FASENRA in asthma is not fully understood.

Ask your doctor about getting a routine blood test that can help determine if you have eosinophilic asthma.

Talking with your doctor about asthma shouldn’t be hard. This discussion guide can help.

While not well defined for severe asthma, elevated blood eosinophils were considered 150 cells/μL or more in this analysis of registry data.


What do eosinophils have to do with asthma?

  • 01 Eosinophils can become active due to common asthma triggers.
  • 02 Active eosinophils can cause inflammation in the lungs.
  • 03 This inflammation can lead to asthma symptoms and asthma attacks.

  • 01 Eosinophils can become active due to common asthma triggers.
  • 02 Active eosinophils can cause inflammation in the lungs.
  • 03 This inflammation can lead to asthma symptoms and asthma attacks.

  • 01 Eosinophils can become active due to common asthma triggers.
  • 02 Active eosinophils can cause inflammation in the lungs.
  • 03 This inflammation can lead to asthma symptoms and asthma attacks.

Eosinophilic asthma and potential health risks.

  • Greater risk icon


    for future asthma attacks

  • Decreased lung function icon


    making it harder to breathe

  • Steroid bottle icon


    like prednisone

Is reliance on oral steroids a problem for you? FASENRA can help you reduce or stop using them.

Complete reduction of daily steroid use was only in patients taking a daily dose of 12.5 mg or less.

Oral steroids like prednisone are used to treat asthma attacks and may control asthma.
But there are several health risks that can occur with long-term use, even at low doses:


Even occasional doses can increase the risk for stomach ulcers, bone fractures, and high blood pressure.

Learn about other ways to treat your asthma.

These are some of the steps you can take to help you find a treatment that works best for you:

  • 01 Start the conversation

    Your primary care doctor can refer you to the right specialist to help you manage your type of asthma, or you can find one here and make an appointment yourself. Then, you can discuss your asthma treatment plan, which includes your current medications, symptom history, and future options, including targeted treatments such as FASENRA.
    Download Discussion Guide

  • 02 Ask for a blood test

    A simple blood test measures your eosinophils. If you’ve had a routine blood test recently, ask your doctor what your blood eosinophil number is.


Do not use FASENRA if you are allergic to benralizumab or any of the ingredients in FASENRA.

Do not use to treat sudden breathing problems.

FASENRA may cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your FASENRA injection. Allergic reactions can sometimes happen hours or days after you get your injection. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:

    • swelling of your face, mouth and tongue

    • breathing problems

    • fainting, dizziness, feeling lightheaded (low blood pressure)

    • rash

    • hives

Before using FASENRA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

  • have a parasitic (helminth) infection.

  • are pregnant or plan to become pregnant. It is not known if FASENRA will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with FASENRA.

    • There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to FASENRA during pregnancy. Healthcare providers can enroll patients or encourage patients to enroll themselves by calling 1-877-311-8972 or visiting www.mothertobaby.org/fasenra.

  • are breastfeeding or plan to breastfeed. It is not known if FASENRA passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use FASENRA.

  • are taking prescription and over-the-counter medicines, vitamins, or herbal supplements.

Do not stop taking your other asthma medicines unless instructed to do so by your healthcare provider.

The most common side effects of FASENRA include: headache and sore throat. These are not all the possible side effects of FASENRA.


FASENRA is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people 12 years and older whose asthma is not controlled with their current asthma medicines. FASENRA helps prevent severe asthma attacks (exacerbations) and may improve your breathing. Medicines such as FASENRA reduce blood eosinophils. Eosinophils are a type of white blood cell that may contribute to your asthma.

FASENRA is not used to treat other problems caused by eosinophils and is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with FASENRA.

It is not known if FASENRA is safe and effective in children under 12 years of age.

Please see accompanying full Prescribing Information including Patient Information and Instructions for Use.

You may report side effects related to AstraZeneca products by clicking here.