FASENRA
FAQ

FASENRA is an add-on maintenance treatment for patients 12 and older with severe eosinophilic asthma. See more

Not for other eosinophilic conditions or sudden breathing problems.

Whether you're already using FASENRA,
or just thinking about it, you’re bound to have some questions.

Here are some answers to important and some of the most common FASENRA questions. If you don’t see your question below, FASENRA 360 provides nurse support*; they may be able to help.
Call today. 1-833-360-HELP (4357)

*Information from our nurses does not replace the advice or training from your physician or other healthcare providers. Nurses cannot provide diagnosis or treatment advice to callers.

Eosinophilic Asthma

What are eosinophils?

Eosinophils are white blood cells that are a normal part of the immune system but can also cause lung inflammation. Nearly 7 out of 10 adults with asthma may have elevated eosinophils, which can be a key cause of asthma. Active eosinophils in the lungs can inflame the airways.

While not well defined for severe asthma, elevated blood eosinophils were considered 150 cells/μL or more in this analysis of registry data.

How do I know if I have eosinophilic asthma?

Your healthcare provider can review your current medications, history with asthma, and breathing tests, as well as measure your eosinophil count with a simple blood test to help determine if your asthma is eosinophilic asthma.

About FASENRA

What is FASENRA?

FASENRA is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people 12 years and older whose asthma is not controlled with their current asthma medicines. FASENRA helps prevent asthma attacks (exacerbations) and may improve your breathing. Medicines such as FASENRA reduce blood eosinophils. Eosinophils are a type of white blood cell that may contribute to your asthma.

FASENRA is not used to treat other problems caused by eosinophils and is not used to treat sudden breathing problems.

The mechanism of action of FASENRA in asthma is not fully understood.

What are the potential benefits of FASENRA?

When added to current asthma treatments, FASENRA has been clinically proven to help:

  • Prevent asthma attacks
  • Improve lung function better than standard asthma medicines alone

For people who rely on oral steroids, FASENRA can help:

  • Lower oral steroid use
  • Some people completely stop using oral steroids§

Your results may vary.

§Complete reduction of daily steroid use was only in patients taking a daily dose of 12.5 mg or less.

How does FASENRA work?

FASENRA is designed to target and remove eosinophils, a key cause of asthma.

The mechanism of action of FASENRA in asthma is not fully understood.

Who should not take FASENRA?

Do not use FASENRA if you are allergic to benralizumab or any of the ingredients in FASENRA. Click here for additional Important Safety Information.

What should I tell my doctor before using FASENRA?

Tell your doctor if you:

  • are taking oral or inhaled corticosteroid medicines
  • have a parasitic (helminth) infection
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed
  • are taking prescription and over-the-counter medicines, vitamins, or herbal supplements

Do not stop taking your other asthma medicines unless instructed to do so by your doctor.

What are the most common side effects?

The most common side effects of FASENRA include: headache and sore throat. These are not all the possible side effects of FASENRA.

Starting FASENRA

How is FASENRA administered?

The FASENRA pre-filled syringe is an injection administered under the skin (subcutaneously) by a healthcare provider. The FASENRA Pen is an injection administered under the skin (subcutaneously) by the patient or their caregiver.

Do not try to inject the FASENRA Pen until you have been trained by your healthcare provider.

How often is FASENRA given?

FASENRA is administered once every 4 weeks for the first three doses, and then once every 8 weeks.

How does FASENRA work with inhalers?

FASENRA is a maintenance medicine and should be added to current treatments.

What happens if I miss a dose?

Each FASENRA dose is very important, so if you miss a dose of FASENRA, call your healthcare provider.

Stay on track with your treatment and help minimize your chances of forgetting a dose. Click here to sign up for dose reminders or a dose calendar.

FASENRA support

How can I get help with insurance questions?

Once you and your doctor decide that FASENRA is right for you, AstraZeneca can check your insurance coverage and help with insurance questions. If you are denied coverage, AstraZeneca still might be able to help. Call to speak with a Personal Reimbursement Counselor at 1-833-360-HELP (4357).

How much does FASENRA cost?

Many factors determine how much you will pay for FASENRA. Sign up now and see if you could pay as little as $0 dollars. The FASENRA Savings Program is for commercially insured patients to cover patient out-of-pocket costs for FASENRA and its administration, up to $13,000 per calendar year.

If you need help paying for FASENRA, AstraZeneca may be able to help. You can get more information on FASENRA affordability programs here.

How can I learn more about available support?

For more information about the range of resources that is available through FASENRA 360, check out the FASENRA Support page, or call 1-833-360-HELP (4357) Monday–Friday, 8 AM to 8 PM, and Saturday–Sunday, 10 AM to 6 PM ET.

Self-Injection

What should I do if my FASENRA Pen does not work?

If the FASENRA Pen fails to administer the dose in its entirety, or simply does not work, call FASENRA 360 at 1-833-360-HELP (4357) and let your healthcare provider know.

What should I do if my FASENRA Pen looks damaged?

If your FASENRA Pen has been frozen, dropped, damaged, or has passed its expiration date, discard the pen in a puncture-resistant Sharps Disposal Container and call FASENRA 360 at 1-833-360-HELP (4357) and let your healthcare provider know.

How do I store my FASENRA Pen?

Store FASENRA in a refrigerator between 36°F to 46°F (2°C to 8°C) in its original carton until you are ready to use it. FASENRA may be kept at room temperature between 68°F to 77°F (20°C to 25°C) for a maximum of 14 days. Once removed from the refrigerator and brought to room temperature, FASENRA must be used within 14 days or thrown away (disposed of).

How do I keep track of my injections?

Building a routine for taking FASENRA is a great way to keep track of your dosing schedule. FASENRA 360 can provide Dose Reminders and a Dose Calendar to help you stay on track with your treatment. Dose reminders can come in the form of text messages, e-mail, or on your calendar. You can sign up and adjust your dose reminders by clicking here or you can call 1-833-360-HELP (4357).

Can someone else administer my FASENRA Pen for me?

Yes, a trained caregiver or healthcare provider can administer your FASENRA injection for you.

If I need help learning how to administer, who can help?

Your healthcare provider should train you in their office. If you would like additional training, you can call FASENRA 360 at 1-833-360-HELP (4357) to speak with one of our nurses or schedule an appointment so they can show you how to do it. You can also watch step-by-step instructions here.

How do I administer my FASENRA Pen?

Click here to read the full instructions for use about how to self-administer your FASENRA Pen. Or, you can also watch a step-by-step instructional video here. Both will show you how to self-administer your FASENRA Pen.

How do I dispose of my used FASENRA Pens?

Put your used FASENRA Pen in a puncture-resistant Sharps Disposal Container right away after use. Do not throw away the FASENRA Pen in your household trash. Throw away the cap and other used supplies in your trash.

Where can I get a sharps container to dispose of used FASENRA Pens?

Only dispose of used or faulty FASENRA Pens in a sharps container, not your household trash. To obtain or replace a puncture-resistant Sharps Disposal Container, call FASENRA 360 at 1-833-360-HELP (4357), or contact your specialty pharmacy.

Where will I get my injection supplies?

Your specialty pharmacy can provide alcohol wipes, and cotton balls or gauze. FASENRA 360 can also provide a Sharps Disposal Container so you can properly dispose of your used FASENRA Pen.

Can I travel with my FASENRA Pen?

Always talk with your healthcare provider before traveling. If you have questions, check the latest TSA guidelines at www.tsa.gov before flying to make sure you’re aware of the most up-to-date information. FASENRA 360 can provide an Insulated Travel Bag to help you travel with your medication.

What do I do if I think I am having an allergic reaction to FASENRA Pen?

If you think you may be having an allergic reaction, seek medical attention immediately. Such reactions may happen within hours or days after the injection. FASENRA can potentially cause serious allergic reactions. You must look out for signs of these reactions (such as hives, rash, breathing problems, fainting, dizziness, feeling lightheaded and/or swelling of your face, tongue, or mouth) while you are taking FASENRA. It is important that you talk to your doctor about how to recognize early symptoms of serious allergic reactions and how to manage these reactions if they occur.

Want to talk to your doctor about FASENRA?
Get a free Discussion Guide to help guide the conversation with your doctor.

IMPORTANT SAFETY INFORMATION

Do not use FASENRA if you are allergic to benralizumab or any of the ingredients in FASENRA.

Do not use to treat sudden breathing problems.

FASENRA may cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your FASENRA injection. Allergic reactions can sometimes happen hours or days after you get your injection. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:

    • swelling of your face, mouth and tongue

    • breathing problems

    • fainting, dizziness, feeling lightheaded (low blood pressure)

    • rash

    • hives

Before using FASENRA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

  • have a parasitic (helminth) infection.

  • are pregnant or plan to become pregnant. It is not known if FASENRA will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with FASENRA.

    • There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to FASENRA during pregnancy. Healthcare providers can enroll patients or encourage patients to enroll themselves by calling 1-877-311-8972 or visiting www.mothertobaby.org/fasenra.

  • are breastfeeding or plan to breastfeed. It is not known if FASENRA passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you use FASENRA.

  • are taking prescription and over-the-counter medicines, vitamins, or herbal supplements.

Do not stop taking your other asthma medicines unless instructed to do so by your healthcare provider.

The most common side effects of FASENRA include: headache and sore throat. These are not all the possible side effects of FASENRA.

APPROVED USE

FASENRA is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people 12 years and older whose asthma is not controlled with their current asthma medicines. FASENRA helps prevent severe asthma attacks (exacerbations) and may improve your breathing. Medicines such as FASENRA reduce blood eosinophils. Eosinophils are a type of white blood cell that may contribute to your asthma.

FASENRA is not used to treat other problems caused by eosinophils and is not used to treat sudden breathing problems. Tell your healthcare provider if your asthma does not get better or if it gets worse after you start treatment with FASENRA.

It is not known if FASENRA is safe and effective in children under 12 years of age.

Please see accompanying full Prescribing Information including Patient Information and Instructions for Use.

You may report side effects related to AstraZeneca products by clicking here.